Insulin action and insulin secretion in polycystic ovary syndrome treated with ethinyl oestradiol/cyproterone acetate
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چکیده
منابع مشابه
Heritability of insulin secretion and insulin action in women with polycystic ovary syndrome and their first degree relatives.
Polycystic ovary syndrome (PCOS), one of the most common endocrine disorders of reproductive age women, is associated with an increased risk of type 2 diabetes mellitus. Defects in both insulin action and insulin secretion contribute to this predisposition to diabetes, but the extent to which these defects are heritable among PCOS families has not been examined. In the present study we used the...
متن کاملTroglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome.
Women with polycystic ovary syndrome (PCOS) are characterized by defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis. We administered the insulin-sensitizing agent troglitazone to 13 obese women with PCOS and impaired glucose tolerance to determine whether attenuation of hyperinsulinemia ameliorates these defects. All subjects had oligomenorrhea, hirsutism, p...
متن کامل[Should insulin resistance be always treated in Polycystic Ovary Syndrome?].
A síndrome dos ovários policísticos (SOP) é a afecção endócrina mais frequente da mulher durante o período reprodutivo, ocorrendo em porcentagens entre 4 e 16% emmulheres com fator familiar importante. Houve muito debate sobre a caracterização desta entidade nos últimos anos. Contudo, o último critério da Society for Androgen Excess estabeleceu que as mulheres deveriam ter hiperandrogenismo (hi...
متن کاملGlucose tolerance, insulin secretion and insulin sensitivity in polycystic ovary syndrome.
Polycystic ovary syndrome (PCOS) is a disorder affecting approximately 5-10% of reproductive aged women [1]. Initially described by Stein and Leventhal in 1935 [2] as a combination of polycystic ovaries, amenorrhoea, hirsutism and obesity, it has been defined in different ways over the years. Finally, in 1990 the National Institutes of Health (NIH) established the new diagnostic criteria for th...
متن کاملInsulin Secretory Defects in Polycystic Ovary Syndrome
The increased prevalence of non-insulin-dependent diabetes mellitus (NIDDM) among women with polycystic ovary syndrome (PCOS) has been ascribed to the insulin resistance characteristic of PCOS. This study was undertaken to determine the role of defects in insulin secretion as well as familial factors to the predisposition to NIDDM seen in PCOS. We studied three groups of women: PCOS with a fami...
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ژورنال
عنوان ژورنال: QJM
سال: 2001
ISSN: 1460-2393
DOI: 10.1093/qjmed/94.1.31